Contact information
+44 (0) 1865 572898
Ileana Badi
PhD
Senior Postdoctoral Researcher
My principal research interests lie in understanding the cellular and molecular mechanisms leading to cardiovascular disease. I obtained my Ph.D. in 2008 at the University of Insubria (Italy), where I studied the role of the transcription factor Ankrd1 in the pathogenesis of the rare congenital heart disease Total Anomalous Pulmonary Venous Return (TAPVR). Hence, I decided to deepen my knowledge on the transcriptional control of cardiac development in Professor Vincent M. Christoffels’s lab at the University of Amsterdam. There, I studied the transcriptional regulation of Tbx3 gene that encodes a transcription factor important for the conduction system and arterial pole morphogenesis. At this point I felt the need to move towards more translational studies; thus, I spent six years at the Centro Cardiologico Monzino, in Milan, where I focused my attention on the role of miR-34a in vascular “inflammaging” and vascular calcification, as this microRNA could be a promising therapeutic target for cardiovascular disease. In June 2018 I joined The Oxford Translational Cardiovascular Research Group, that superbly combines basic science and clinical research. Here, I am keen on studying how the cross-talk between adipose tissue and the cardiovascular system can affect cardiovascular disease.
Key publications
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Journal article
Carena MC. et al, (2023), J Am Coll Cardiol, 82, 317 - 332
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Journal article
Kondo H. et al, (2021), Eur Heart J, 42, 4947 - 4960
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Journal article
Badi I. and Antoniades C., (2021), Circulation, 143, 160 - 162
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Journal article
Akoumianakis I. et al, (2020), Sci Transl Med, 12
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Journal article
Badi I. et al, (2018), Arterioscler Thromb Vasc Biol, 38, 2079 - 2090
Recent publications
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Journal article
Carena MC. et al, (2023), J Am Coll Cardiol, 82, 317 - 332
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Genetic variability of lipoprotein(a) controls vascular inflammation/redox signalling and predicts adverse cardiovascular outcomes in coronary artery disease N.
Journal article
Polkinghorne MD. et al, (2023), EUROPEAN HEART JOURNAL, 44
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Human epicardial adipose tissue-secreted miR-92a-3p regulates myocardial redox state via paracrine signalling: implications for cardiovascular clinical outcomes
Journal article
Badi I. et al, (2023), EUROPEAN HEART JOURNAL, 44
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Journal article
Kotanidis CP. et al, (2022), Lancet Digit Health, 4, e705 - e716
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Journal article
Badi I. et al, (2022), Frontiers in Cell and Developmental Biology, 10