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Pramila Rijal

DPhil

COI Career Development Fellow

Antibodies, Vaccine and Drug against Influenza virus

Antibodies and Vaccine Development Against Infectious Viruses

Dr. Pramila Rijal is a researcher focused on infectious diseases, particularly Influenza and Ebola viruses. She received her Ph.D. from the University of Oxford in 2017, where she studied the human monoclonal antibody response to these viruses after natural infection and vaccination. With over ten years of research experience, Dr. Rijal has developed expertise in antibody and vaccine development. Her current work centres on the influenza neuraminidase (NA) protein, which is crucial for developing effective treatments and vaccines.

Research Focus

Dr. Rijal's research includes:

  1. Antibody Refinement: Improving monoclonal antibodies in vitro to improve their effectiveness against influenza viruses.
  2. Vaccine Development: NA-based nanoparticle vaccines aimed at potentially pandemic influenza strains.
  3. Drug Discovery: Identifying new drugs that target the neuraminidase protein to advance antiviral therapies.

The funding support comes from the CAMS-Oxford Institute and the Novo-Nordisk Foundation. 

https://www.camsoxford.ox.ac.uk/research/groups/rijal-group