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Little is known about the inflammasome beyond its function in innate immune response. In this issue of Immunity, Tyrkalska et al. report that the inflammasome regulates the balance between erythroid and myeloid differentiation in model systems, providing insights into hematopoietic lineage bias associated with inflammatory conditions.

Original publication

DOI

10.1016/j.immuni.2019.06.022

Type

Journal article

Journal

Immunity

Publication Date

16/07/2019

Volume

51

Pages

3 - 5

Keywords

GATA1 Transcription Factor, Hematopoiesis, Immunity, Innate, Inflammasomes, NLR Family, Pyrin Domain-Containing 3 Protein