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Curry Group: Endothelial regulation of haemostasis in health and disease
We study the mechanisms by which vascular endothelial cells regulate haemostasis in health and in acquired bleeding disorders, namely trauma-induced coagulopathy, to better understand disease pathogenesis and identify novel therapeutic targets.
Zimmermann Group: Iron Nutrition - Stable Isotopes and Therapeutics
The overall aim of our research program is to improve iron nutrition and reduce anaemia in women and children, directly supporting the U.N.'s 2030 Sustainable Development Goal of ‘Zero Hunger’.
Lapidaire Group: Brain Health Vascular Imaging
Our group aims to make early diagnosis and continuous check-ups for (vascular) diseases accurate, affordable, and accessible for everyone. We focus on women’s vascular health and global health and aim to better understand the impact of hypertensive disorders of pregnancy on the brain.
Valkovič Group: Body MRS Group
Pushing the Limits of Multi-nuclear Magnetic Resonance Spectroscopy of the Heart, Liver and Muscle
Zhang Group: Artificial Intelligence in Cardiovascular Imaging
We work with clinicians and MR scientists on a day-to-day basis to develop novel AI machine-learning approaches for cardiovascular imaging.
Akbar Group: Extracellular Vesicles in Cardiovascular, Inflammatory and Metabolic Disease
The Akbar Lab is interested in defining the therapeutic and diagnostic potential of extracellular vesicles for immunomodulation and precision medicine in cardiovascular, metabolic, and inflammatory diseases.
Goel Group: Cardiovascular genetics and bioinformatics
We have performed a number of genome-wide association analyses and meta-analyses on different case/control phenotypes and quantitative traits. After discovering genetic loci, our main interest is to refine the locus for causal variants using different computational approaches and integrating epigenetic dat…
Tyler Group
Development and Application of Cardiac Magnetic Resonance Imaging and Spectroscopy
Pavlides Group: Quantitative MR and liver disease
Our group investigates how MR techniques can be used to improve the care of patients with liver disease. The scope of our work is broad and ranges from evaluation of mature MR techniques in large multicentre studies, to proof-of-concept studies using new methods, or new clinical applications of existing tec…
Holloway Group: Microfluidic Neurological Models (MNM)
The Oxford MNM group focuses on developing in vitro models for neurological disease. Employing micro-fabrication techniques to define channels and features in cell culture devices at the scale of the cell and below, opens up the opportunity to shape cellular microenvironments to better reflect those foun…
Cancer target identification and development
Our research interests lie in studying the molecular mechanisms of tumour growth and the target development. We focus on the impact of metabolism and epigenetic regulation on crosstalk between stromal cells and tumour cells in the tumour microenvironment. The ongoing investigated tumours include color…
Hodson Group: Cellular Metabolism and GPCR Signalling
We investigate how cellular metabolism and GPCR signaling converge to influence energy homeostasis in the periphery and brain during health and metabolic disease. We develop novel tools and technologies that allow us to study cell and tissue function with exquisite accuracy and detail, and apply these approac…
Koohy Group: Machine Learning and Integrative Approaches in Immunology
- Investigative Medicine Division
- MRC Translational Immune Discovery Unit
- MRC Weatherall Institute of Molecular Medicine
We would like to understand the functional and molecular mechanisms of the immune system in various immunologically important conditions such as cancer, infection, autoimmune disease as well as ageing. We have a special interest in computational cancer immunotherapy such as antigen presentation,…
Toepfer Group: Cardiac Physiology and Disease Modeling
Understanding key mechanisms that govern cardiac muscle function in health and disease
Wilkinson Group: Blood Stem Cell Expansion and Fitness
Haematopoietic stem cells (HSCs) support blood cell production throughout life and are also used clinically in cell and gene therapies. We are studying the biology of this important stem cell population with the aim of developing new HSC-based therapies.
Simmons Group: Intestinal Immunity in Health and Disease
We define how the immune system functions in the intestine to promote health. We uncover the immune pathogenesis of intestinal diseases such as inflammatory bowel disease to develop better ways to treat these disorders.