Akbar Group: Extracellular Vesicles in Cardiovascular, Inflammatory and Metabolic Disease
The Akbar Lab is interested in defining the therapeutic and diagnostic potential of extracellular vesicles for immunomodulation and precision medicine in cardiovascular, metabolic, and inflammatory diseases.
We have a particular interest in how endothelial cell derived extracellular vesicles mediate long range communication across organs, and how we can capitalise on this signalling for targeted therapeutics and diagnosis. We employ state of the art techniques in extracellular vesicle isolation and characterisation, using translational approaches of highly characterised clinical cohorts to derive hypothesis driven in vitro and in vivo studies using model systems.
DPhil Students
Current
Dann Paget
Lewis Timms
Amaury Genovese
Complete
2019 Laurienne Edgar
Masters Students
Current
Amber Wilkins
Undergraduate Final Honours School Students
Current
Divya Ganesh
Complete
2022 Raphaella Ridley
2019 Charlotte Lee
2018 Jonathan Martin
2018 Eleanor Hogg
2017 Tanvir Rafe
Latest publications
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Decision-Making for Preventive Interventions in Asymptomatic Patients.
Journal article
Raabe A. et al, (2024), Stroke, 55, 1951 - 1955
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Building the Glucagon-Like Peptide-1 Receptor Brick by Brick: Revisiting a 1993 Diabetes Classic by Thorens et al.
Journal article
Thorens B. and Hodson DJ., (2024), Diabetes, 73, 1027 - 1031
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Accelerated 3D multi-channel B 1 + mapping at 7 T for the brain and heart.
Journal article
Kent JL. et al, (2024), Magn Reson Med
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Estimating Risk Factor Time Paths Among People with Type 2 Diabetes and QALY Gains from Risk Factor Management
Journal article
Gao N. et al, (2024), PharmacoEconomics