Investigative Medicine Division
We aim to rapidly translate innovative science into patient benefit across a range of disease areas. From molecular biology and target discovery, through to interventional medicine and informing policy, we bring together researchers in a diverse range of specialties including acute stroke, dementia and immunology.
Head of Division
Latest publications
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Goblet cell differentiation subgroups in colorectal cancer.
Journal article
Abdullayeva G. et al, (2024), Proc Natl Acad Sci U S A, 121
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Temporal changes in erythroid progenitors in critically ill patients: a prospective cohort study
Journal article
Scott C. et al, (2024), Haematologica
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Salmonella Typhimurium screen identifies shifts in mixed-acid fermentation during gut colonization.
Journal article
Nguyen BD. et al, (2024), Cell host & microbe, 32, 1758 - 1773.e4
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Development of a recombinant non-replicating Newcastle disease virus.
Journal article
Cheow P-S. et al, (2024), Avian Pathol, 1 - 9
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Safety in spinal surgery—Empowering clinicians to report concerns in motor function
Journal article
Burrows J. et al, (2024), Journal of Advanced Nursing
Specific research groups include:
The Buchan Group's Laboratory of Cerebral Ischemia is a pre-clinical research group aiming to uncover mechanisms of cell death in stroke, and develop novel strategies to reduce this. Group members have also developed in-vitro models for neurological diseases.
The MRC Translational Immune Discovery Unit (TIDU) aims to uncover the molecular pathways driving immune-mediated diseases – researchers in the unit develop and harness new technologies to map the causes and molecular drivers of a series of inflammatory disorders in order to develop better ways to treat them.
Professor Alison Simmons is the Head of Investigative Medicine.
Researchers have major collaborations with the MRC, the Wellcome Trust, CRUK and the NIHR, as well as cross-departmental collaborations such as Human Iron Research at Oxford (HIRO).
Latest news
Welcome to the new RDM Visiting Professors
27 November 2023