Oxford Centre for Diabetes, Endocrinology and Metabolism

OCDEM is a pioneering centre that combines clinical care, research and education in diabetes, endocrine and metabolic diseases. By promoting world-class research, we aim to enhance understanding of these diseases and to accelerate the search for new treatments and cures.

Head of OCDEM

David Ray

Professor of Endocrinology, Head of OCDEM, and Co-Director Sir Jules Thorn Sleep and Circadian Neuroscience Institute

david.ray@ocdem.ox.ac.uk

History

Read about the beginnings of our centre.

Find out more

Latest publications

Characterization of quinazolinone calcilytic therapy for autosomal dominant hypocalcemia type 1 (ADH1).
Hannan FM. et al, (2025), J Biol Chem
Effects of aspirin and omega-3 fatty acids on age-related macular degeneration in ASCEND-Eye: a randomised placebo-controlled trial in a population with diabetes.
Sammons E. et al, (2025), BMJ Open, 15
LRP5 promotes adipose progenitor cell fitness and adipocyte insulin sensitivity.
Loh NY. et al, (2025), Commun Med (Lond), 5
A silicon rhodamine-fused glibenclamide to label and detect malaria-infected red blood cells
HODSON D., (2025), ChemBioChem

Patient undergoing a DEXA scan

OCDEM is one of the largest dedicated research centres in diabetes, endocrinology and metabolism in Europe. Led by Professor David Ray, our work spans the spectrum of basic, translational and patient-orientated research. We are closely integrated with excellent clinical care for patients with diabetes, metabolic and endocrine conditions.

Areas of strength

Type 2 diabetes including genomics, islet biology and function, novel therapeutics and large-scale clinical trials providing evidence for best practise
Human integrative metabolic physiology
Endocrine disorders such as glucocorticoid action, pituitary tumours and calcium homeostasis