Diabetes Trials Unit
The Diabetes Trials Unit (DTU) is a UKCRC accredited clinical trials unit specialising in performing local, national and multinational clinical trials related to treating and managing diabetes and other cardiometabolic and related conditions. We work collaboratively with researchers and organisations to support trials and other studies.
What's new
Under-40s diagnosed with type 2 diabetes have a mortality rate four times higher than the general population
24 October 2024
People diagnosed with type 2 diabetes before 40 years of age, have nearly four times the risk of death compared with the general UK population, a new study carried out at the University of Oxford’s Radcliffe Department of Medicine has found.
Hydroxychloroquine provides moderate COVID-19 prevention
16 September 2024
COPCOV, the world’s largest COVID-19 chemoprevention study, published results today showing that hydroxychloroquine (HCQ) has a moderate benefit in preventing COVID-19. The COPCOV trial was led globally by the Mahidol Oxford Tropical Medicine Research Unit (MORU), Thailand. The Diabetes Trials Unit (DTU) was the UK coordinating centre for the trial, helped develop the protocol, and was responsible for managing UK sites, approvals and procedures.
Patients receiving steroids are more than twice as likely to develop diabetes, UK study has found
10 September 2024
Patients who are being treated with systemic glucocorticoids are more than twice as likely to develop diabetes as those not receiving the treatment, a new study by researchers at the Radcliffe Department of Medicine’s Diabetes Trial Unit has found.
Early blood glucose control for people with type 2 diabetes is crucial for reducing complications and prolonging life
18 May 2024
Research led by scientists from the Universities of Oxford and Edinburgh has found that early good blood glucose control can minimise the lifetime risk of diabetes-related complications, including heart attacks, kidney failure and vision loss.
The LEGEND-D Trial – which aims to prevent low blood sugar levels in type 1 diabetes – is open to recruitment
16 April 2024
The first participant has completed initial study activities and is now randomised to one of the trial’s arms.
Latest publications
Paediatric traumatic brain injury: clinical presentation, treatment approaches, management strategies, and outcomes. Insights from the CENTER-TBI study
Journal article
Graziano F. et al, (2026), Journal of Anesthesia Analgesia and Critical Care, 6
Limited representation of authors from low- and middle-income countries in trials with participants from LMICs across 15 years (2008–2023)
Journal article
Marwah HK. et al, (2026), Journal of Clinical Epidemiology, 196, 112336 - 112336
TiO2 Alternative Coatings for Ferric Pyrophosphate Premixes: Stability and Bioaccessibility Relative to Ferrous Fumarate
Journal article
Teichman DL. et al, (2026), Innovative Food Science and Emerging Technologies, 111
Association between urban ecological environment quality, socioeconomic disparity, and incidence of type 2 diabetes among middle-aged and elderly populations in the United Kingdom
Journal article
Gu J. et al, (2026), Landscape and Urban Planning, 271
The regulation of intrahepatic fatty acid partitioning within the human liver: the effect of sex.
Journal article
Dennis KMJH. et al, (2026), Clin Sci (Lond), 140, 1035 - 1054
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