Programme
SUNDAY |
Download the final programme here31ST March 2019
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If you have reserved accommodation at St Catherine's College you can check in from 2pm GMT at the Porter's Lodge. There are no social events planned for Sunday evening however, there are plenty of good restaurants and pubs in the centre of Oxford to hang out in. |
MONDAY |
1ST APRIL 2019 |
From: 8:00am |
REGISTRATION |
8:30-10.30am |
SESSION 1: Islet Cell Dysfunction in autoimmune DiabetesChair: Sarah Richardson [UK] |
8.30-9.00am |
Current status of Type 1 diabetes John Todd [UK] |
9.00-9.30am |
Development of new immunomodulatory prevention strategies Caroline Daniel [Germany] |
9.30-10.00am |
Monogenic forms of autoimmune diabetes Sarah Flanagan [UK] |
10.00-10.30am |
OP1 A Map of Human Type 1 Diabetes Progression by Imaging Mass Cytometry Nicolas Damond [Switzerland] OP2 A Human Induced Pluripotent stem cell based in vitro model for autoimmune Type 1 Diabetes Elad Sintov [USA] |
10:30-11:00am |
COFFEE BREAK & POSTERS |
11:00 -1:00pm |
SESSION 2: Islet Cell Dysfunction in non-autoimmune DiabetesChair: Maureen Gannon [USA] |
11:00am |
ER Stress: Beta-Cells Rise to the Challenge Laura Alonso [USA] |
11.30-12.00pm |
Modelling PTF1A enhancer mutations which cause diabetes in mice Irene Miguel-Escalada [Spain] |
12.00-12.30pm |
SLC30A8 effects on beta-cell function Tinnamaia Tumoi [Finland] |
12.30-1.00pm |
OP3 Molecular Clockwork of Human Islets from Type 2 Diabetes Volodymyr Petrenko [Switzerland] OP4 GLP-1 analogs prevent and revert diabetes in Wolfram Syndrome Maria Igoillo Esteve [Belgium] |
1:00-2:00pm |
LUNCH BREAK |
2:00-4:00pm |
SESSION 3: Islet Signalling & insulin secretionChair: Anders Tengholm [Sweden] |
2:00-2.30pm |
Mechanisms underlying early beta-cell dysfunction leading to loss of beta-cell identify in diabetes Maria Remedi [USA] |
2.30-3.00pm |
Insulin and glucagon granule behaviour in Type 2 diabetes Sebastian Barg [Sweden] |
3.00-3.30pm |
Using conditional approaches to understand alpha-, beta- and delta-cell functional subpopulations David Hodson [UK] |
3.30-4.00pm |
OP5 IGF Receptor-like 1 is a novel regulator of insulin signalling pathway Heiko Lickert [Germany] OP6 Hub cells co-ordinate 3 dimensional beta-cell Ca2+ dynamics in mouse islets in vivo Victoria Salem [UK] |
4:00-4:30pm |
TEA BREAK & POSTERS |
4:30-5:30pm |
SESSION 4: KEYNOTE LECTURE 1 - Chair: Anna Gloyn [uk]
The Changing Beta-Cell Susan Bonner-Weir [USA] |
5:30-7:00pm |
POSTERS & DRINK reception in the common room |
7:00pm |
DINNER in College |
TUESDAY |
2nd APRIL 2019 |
8:30 - 10.30am |
SESSION 5: Epigenetics & Genomics of Islet CellsChair: Lorenzo Pasquali [Spain] |
8.30-9.00am |
Connecting human islet cell functional & transcriptomic heterogeneity by combined patch-clamp and scRNA-seq Patrick MacDonald [Canada] |
9.00-9.30am |
Epigenomics of diabetic islets Tiina Ronn [Sweden] |
9.30-10.00am |
Single Cell characterisation of islet cells Andrew Pospisilik [Germany/USA] |
10.00-10.30am |
OP7 A novel method enabling background-free purification of age-distinct insulin secretary granules for proteomic and lipidomic analysis Martin Neukam [Germany] OP8 Chromatin Interactions aid identification of effector transcripts in type 2 diabetes GWAS loci in beta-cells Vibe Nylander [UK] |
10:30-11:00am |
COFFEE BREAK & POSTERS |
11:00am-1:00pm |
SESSION 6: Modelling mutations in beta-cell modelsChair: Adrian Teo [Singapore] |
11:00-11.30am |
Modelling INS gene mutations in human IPSCs Timo Otontoski [Finland] |
11.30-12.00 |
Identifying mechanisms for T2D GWAS variants in IPSCs Nicole Krentz [UK] |
12.00-12.30pm |
Understanding regulatory variation in beta-cell development Maike Sander [USA] |
12.30-1.00pm |
OP9 A 3D analysis of the structural and functional beta-cell architecture in human pancreatic islets Louise Cottle [Australia] OP10 4 D imaging of insulin secretory granule dynamics and secretion in primary beta cells with lattice light sheet microscopy Andreas Mueller [Germany] |
1:00-2:00pm |
LUNCH BREAK |
2:00-4:00pm |
SESSION 7: Islet -Cell Models & TherapiesChair: Jean-Christophe Jonas [Belgium] |
2:00-2.30pm |
The EndoCBH Cell family Raphael Scarfmann [France] |
2.30-3.00pm |
In vitro methods for pancreatic progenitors M. Christina Nostro [Canada] |
3.00-3.30pm |
Designing human islet cells Holger Russ [USA] |
3.30-4.00pm |
OP11 Manipulating differentiation dynamics of endocrine cells from human pluripotent stem cell derived pancreatic progenitors Yung Hae Kim [Denmark] OP12 PRMT1 maintains mature beta-cell identify by histone arginine methylation Jooyub Lee [Korea] |
4:00-4:30pm |
EASD ISG AssemblyFran Ashcroft [UK] |
4.30-5.30pm |
TEA & POSTERSPRESENTERS PLEASE REMOVE YOUR POSTER AT THE END OF THIS SESSION |
6:30-8.00pm |
OXFORD ASHMOLEan MUSEUM VISIT (DRINKS & canapéS)COACHES FROM THE PORTERS LODGE |
8.00pm
8:30pm |
PRE DINNER DRINKS available in THE SENIOR COMMON ROOMFORMAL HALL (DINNER) - dress code smart casual
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WEDNESDAY |
3RD APRIL 2019 |
From 8:30am |
SESSION 8: Beta-Cell DevelopmentChair: Lori Sussel [USA] |
8.30-9.00am |
Zebrafish as a model for understanding beta-cell development Nikolay Ninov [Germany] |
9.00-9.30am |
Beta-Cell Development Senta K Georgia [USA] |
9.30-10.00am |
Neonatal Diabetes due to a failure of beta-cell development Elisa De Franco [UK] |
10.00-10.30am |
Feedback and self-assembly principles in pancreatic endocrine-cell birth and islet clustering Chris Wright [USA] |
10:30-11:00am |
COFFEE BREAK |
11:00am-1:30pm |
SESSION 9: Overview & Update on Collaborative Initiatives in Islet Cell Function & DiabetesChair: Ben Glaser [Israel] |
11:00-11.30am |
STEMBANCC (IMI) Christian Honore [Denmark] |
11.30-12.00 |
RHAPSODY (IMI) Michele Solimena [Germany] |
12.00-12.30 |
T2DSYSTEMS (Horizon 2020) Miriam Cnop [Belgium] |
12.30-13.00 |
INNODIA (IMI): Acknowledging the dialogue between the immune system and the beta-cell in T1D Chantel Mathieu [Belgium] |
1:00 - 2:00pm |
LUNCH BREAK |
2:00-3:00pm |
Session 10. KEYNOTE LECTURE 2 - CHAIR LENA Eliasson (Sweden)
Integration of human genetics and islet genomics to advance understanding and management of type 2 diabetes Mark McCarthy (UK) |
3.00-3.30pm | MEETING CLOSE |