Daniel Royston and Rosalin Cooper from our Nuffield Division of Clinical Laboratory Sciences have made a successful application to the 2024 MPN Challenge. They have received a grant of $200,000 over two years for their project 'Spatial transcriptomic analysis of the bone marrow landscape: a novel approach to improve AI-based assessment in MPN'. They are one of six projects selected from among 45 applications.
Project goals
Myeloproliferative neoplasms (MPNs) are a closely related group of chronic, progressive blood cancers in which the bone marrow typically overproduces one of the mature blood elements.
The goal of the funded project is to develop new and improved artificial intelligence (AI) tools to better diagnose and provide much more information about what goes wrong in the bone marrow of MPN patients. It will help to find out which appearances in the bone marrow are important when planning treatment, and allow the care team to decide which new treatments may be most effective.
The team will work closely with patient groups to help MPN patients to better understand the results of their bone marrow biopsies.