Contact information
Research groups
Websites
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MRC Molecular Haematology Unit
Research Unit
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MRC Weatherall Institute of Molecular Medicine
Institute
Aude-Anais Olijnik French
BSc Cell Biology and Physiology, MSc Microbiology and Omics
Senior Research Assistant
- Cell biology
- Organoids
- Assay development
- Translational medicine
- Research skills
My current work focuses on the generation of induced pluripotent stem cell (iPSC)-derived bone marrow organoids to further our understanding of haematological malignancies, with a specific focus on myeloproliferative neoplasms (MPNs), and support the development of therapies through target validation and small molecule screens.
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My previous research projects were aimed at understanding the molecular basis of a rare type of anaemia called Congenital Dyserythropoietic Anaemia type I (CDA-I) (under the supervision of Prof. Veronica Buckle, Dr. Christian Babbs and Dr. Noémi Roy) and investigating the possible reactivation of an embryonic globin gene as treatment for alpha-thalassaemia patients (under the supervision of Prof. Doug Higgs and Dr. Christian Babbs).
Recent publications
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Generating human bone marrow organoids for disease modeling and drug discovery.
Journal article
Olijnik A-A. et al, (2024), Nat Protoc
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Data from Human Bone Marrow Organoids for Disease Modeling, Discovery, and Validation of Therapeutic Targets in Hematologic Malignancies
Other
Khan AO. et al, (2023)
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Data from Human Bone Marrow Organoids for Disease Modeling, Discovery, and Validation of Therapeutic Targets in Hematologic Malignancies
Other
Khan AO. et al, (2023)