Contact information
Research groups
Francesco Pezzella
FRCP
Professor of Tumour Pathology
- Consultant Pathologist
Cancer and blood vessels interaction, the biology of non-angiogenic tumours
The CRUK Tumour Pathology Group is an integral part of the CRUK Oxford Cancer Centre directed by Professor Adrian Harris. It exists to provide academic pathology support to the other constituent groups within that centre and to perform independent research. Currently the major topic of the group concerns tumour angiogenesis, hypoxia and cell cycle. Each member of the group has specific projects that are reviewed at the weekly unit meetings and include the production of monoclonal antibodies, immunohistochemistry, in situ hybridisation and the use of DNA and tissue microarrays.
Key publications
-
Evidence Showing That Tumors Can Grow Without Angiogenesis and Can Switch Between Angiogenic and Nonangiogenic Phenotypes.
Journal article
Pezzella F. and Gatter KC., (2016), J Natl Cancer Inst, 108
-
When cancer co-opts the vasculature.
Journal article
Pezzella F. and Harris AL., (2014), N Engl J Med, 370, 2146 - 2147
Recent publications
-
Low cytoplasmic NUB1 protein exerts hypoxic cell death with poorer prognosis in oestrogen receptor negative breast cancer patients.
Journal article
Tan K-L. et al, (2024), Transl Oncol, 49
-
Accessing the vasculature in cancer: revising an old hallmark.
Journal article
Harris AL. et al, (2024), Trends Cancer
-
On coalescent angiogenesis and the remarkable flexibility of blood vessels.
Journal article
Pezzella F. and Kerbel RS., (2022), Angiogenesis
-
Dissecting the heritable risk of breast cancer: From statistical methods to susceptibility genes.
Journal article
Fanfani V. et al, (2020), Semin Cancer Biol
-
Early squamous cell lung carcinoma: prognostic biomarkers for the many.
Journal article
Pezzella F., (2019), Thorax, 74, 527 - 528