Contact information
Colleges
Lucia Moreira
Postdoctoral Researcher
I am a Postdoctoral Researcher in the Division of Cardiovascular Medicine, and hold a DPhil in Medical Sciences.
My research focuses on the molecular mechanisms driving atrial fibrillation (AF). Despite its prevalence, the structural and electrical remodelling underlying AF remains incompletely understood. My work aims to identify key pathways involved in AF-related remodelling and uncover potential therapeutic targets.
A central aspect of my research is investigating the role of the hormone Calcitonin, the calcitonin receptor (CTR) and its downstream signalling pathways in atrial remodelling and arrhythmogenesis. By advancing our understanding of calcitonin signalling and atrial remodelling, we aim to support the development of targeted therapies that could improve patient outcomes and reduce the global burden of AF.
Recent publications
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Single-nucleus multi-omics implicates androgen receptor signaling in cardiomyocytes and NR4A1 regulation in fibroblasts during atrial fibrillation.
Leblanc FJA. et al, (2025), Nat Cardiovasc Res
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Aging-associated mechanisms of atrial fibrillation progression and their therapeutic potential
Zhao S. et al, (2024), Journal of Cardiovascular Aging, 4
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Rare Variant in MRC2 Associated With Familial Supraventricular Tachycardia and Wolff-Parkinson-White Syndrome.
Potter AS. et al, (2024), Circ Genom Precis Med
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Targeting Calpain-2-mediated Junctophilin-2 cleavage delays heart failure progression following myocardial infarction.
Lahiri SK. et al, (2024), J Mol Cell Cardiol
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ELTD1 Activation Induces an Endothelial-EMT Transition to a Myofibroblast Phenotype.
Sheldon H. et al, (2021), Int J Mol Sci, 22