Rosalin Cooper
MBChB BMedSc MSt DPhil FRCPath
Clinical Lecturer in Histopathology
I am an academic Histopathologist. My research explores how the cellular microenvironment in the bone marrow underpins the development of blood cancer. We use multi-modal spatial analysis, including spatial transcriptomic approaches, to characterise the bone marrow in both health and disease. Our work has a strong translational focus, and we aim to identify features which have the potential to facilitate more objective diagnosis and prediction, and for monitoring treatment response for patients with blood cancer. We also explore how to best develop and apply AI-based image analysis algorithms within both research and clinical workflows.
I completed my DPhil at the University of Oxford in 2022, during which I used bulk and single cell RNA-seq and epigenetic cell-free DNA profiling to characterise peripheral immune responses to immune checkpoint blockade. I have undertaken clinical training in Birmingham, Southampton and Oxford.
My research is funded by the Jean Shanks Foundation, the Pathological Society and MPN Research Foundation.
Recent publications
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Spatial transcriptomic approaches for characterising the bone marrow landscape: pitfalls and potential.
Journal article
Cooper RA. et al, (2024), Leukemia