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The present invention discloses an engineered bacteriophage comprising a polynucleotide encoding a heterologous protein under the control of a repressible promoter. Also disclosed are processes for producing the engineered bacteriophage, pharmaceutical compositions comprising the engineered bacteriophage and methods of treatment using the engineered bacteriophage.

Type

Publication Date

20/03/2025

Addresses

Maria Ababi, University of Warwick, Warwick Medical School, Coventry, United Kingdom