A human genome editing-based MLL::AF4 B-cell ALL model recapitulates key cellular and molecular leukemogenic features.
Bueno C. et al, (2023), Blood
Temporal analyses reveal a pivotal role for sense and antisense enhancer RNAs in coordinate immunoglobulin lambda locus activation.
Gao Z. et al, (2023), Nucleic Acids Res
MLL-AF4 cooperates with PAF1 and FACT to drive high-density enhancer interactions in leukemia.
Crump NT. et al, (2023), Nat Commun, 14
Author Correction: Capture-C: a modular and flexible approach for high-resolution chromosome conformation capture.
Downes DJ. et al, (2023), Nat Protoc
Capture-C: a modular and flexible approach for high-resolution chromosome conformation capture.
Downes DJ. et al, (2022), Nat Protoc
DOT1L inhibition reveals a distinct subset of enhancers dependent on H3K79 methylation.
Godfrey L. et al, (2019), Nat Commun, 10
Cut-and-Run: A Distinct Mechanism by which V(D)J Recombination Causes Genome Instability.
Kirkham CM. et al, (2019), Mol Cell, 74, 584 - 597.e9
The ESC: The Dangerous By-Product of V(D)J Recombination.
Smith AL. et al, (2019), Front Immunol, 10