Publications — Radcliffe Department of Medicine

Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

HSV-1 employs UL56 to antagonize expression and function of cGAMP channels.

Blest HTW. et al, (2024), Cell Rep, 43

Varicella-Zoster virus ORF9 is an antagonist of the DNA sensor cGAS.

Hertzog J. et al, (2022), EMBO J, 41

Interferon induction held captive in tumor cells.

Bridgeman A. and Rehwinkel J., (2021), Mol Cell, 81, 4109 - 4110

Adenosine-to-inosine editing of endogenous Z-form RNA by the deaminase ADAR1 prevents spontaneous MAVS-dependent type I interferon responses.

Tang Q. et al, (2021), Immunity, 54, 1961 - 1975.e5

Inclusion of cGAMP within virus-like particle vaccines enhances their immunogenicity.

Chauveau L. et al, (2021), EMBO Rep, 22

Chemotherapy-induced transposable elements activate MDA5 to enhance haematopoietic regeneration.

Clapes T. et al, (2021), Nat Cell Biol, 23, 704 - 717

The RNA sensor MDA5 detects SARS-CoV-2 infection.

Sampaio NG. et al, (2021), Sci Rep, 11

RIG-I Plays a Dominant Role in the Induction of Transcriptional Changes in Zika Virus-Infected Cells, which Protect from Virus-Induced Cell Death.

Schilling M. et al, (2020), Cells, 9

SAMHD1 Limits the Efficacy of Forodesine in Leukemia by Protecting Cells against the Cytotoxicity of dGTP.

Davenne T. et al, (2020), Cell Rep, 31

cGAMP loading enhances the immunogenicity of VLP vaccines

Chauveau L. et al, (2020)

Deoxyguanosine is a TLR7 agonist.

Davenne T. et al, (2020), Eur J Immunol, 50, 56 - 62

Innate immune sensing of cytosolic chromatin fragments through cGAS promotes senescence.

Glück S. et al, (2017), Nat Cell Biol, 19, 1061 - 1070

Sensing of viral and endogenous RNA by ZBP1/DAI induces necroptosis.

Maelfait J. et al, (2017), EMBO J, 36, 2529 - 2543

Purification of Cyclic GMP-AMP from Viruses and Measurement of Its Activity in Cell Culture.

Mayer A. et al, (2017), Methods Mol Biol, 1656, 143 - 152

Vector delivery-dependant effect of human tissue plasminogen activator signal peptide on vaccine induction of T cells

Hanke T. et al, (2016), Journal of HIV and AIDS

Restriction by SAMHD1 Limits cGAS/STING-Dependent Innate and Adaptive Immune Responses to HIV-1.

Maelfait J. et al, (2016), Cell Rep, 16, 1492 - 1501

Viruses transfer the antiviral second messenger cGAMP between cells.

Bridgeman A. et al, (2015), Science, 349, 1228 - 1232

Transient IL-10 receptor blockade can enhance CD8(+) T cell responses to a simian adenovirus-vectored HIV-1 conserved region immunogen.

Clutton G. et al, (2015), Hum Vaccin Immunother, 11, 1030 - 1035

Characterization of T-cell responses to conserved regions of the HIV-1 proteome in BALB/c mice.

Ondondo B. et al, (2014), Clin Vaccine Immunol, 21, 1565 - 1572

Vaccine-elicited human T cells recognizing conserved protein regions inhibit HIV-1.

Borthwick N. et al, (2014), Mol Ther, 22, 464 - 475

Load More

Include forthcoming?