Publications — Radcliffe Department of Medicine

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Discovery of biomarkers for glycaemic deterioration before and after the onset of type 2 diabetes: descriptive characteristics of the epidemiological studies within the IMI DIRECT Consortium.

Koivula RW. et al, (2019), Diabetologia, 62, 1601 - 1615

Comparative performances of machine learning methods for classifying Crohn Disease patients using genome-wide genotyping data.

Romagnoni A. et al, (2019), Sci Rep, 9

Plasma Fucosylated Glycans and C-Reactive Protein as Biomarkers of HNF1A-MODY in Young Adult-Onset Nonautoimmune Diabetes.

Juszczak A. et al, (2019), Diabetes Care, 42, 17 - 26

Type 2 diabetes risk alleles in PAM impact insulin release from human pancreatic β-cells.

Thomsen SK. et al, (2018), Nat Genet, 50, 1122 - 1131

A Genome-Wide Association Study of Diabetic Kidney Disease in Subjects With Type 2 Diabetes.

van Zuydam NR. et al, (2018), Diabetes, 67, 1414 - 1427

Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls.

Flannick J. et al, (2018), Sci Data, 5

Integrative network analysis highlights biological processes underlying GLP-1 stimulated insulin secretion: A DIRECT study.

Gudmundsdottir V. et al, (2018), PLoS One, 13

Sequence data and association statistics from 12,940 type 2 diabetes cases and controls.

Flannick J. et al, (2017), Sci Data, 4

A Genome-Wide Association Study of IVGTT-Based Measures of First-Phase Insulin Secretion Refines the Underlying Physiology of Type 2 Diabetes Variants.

Wood AR. et al, (2017), Diabetes, 66, 2296 - 2309

A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk.

Manning A. et al, (2017), Diabetes, 66, 2019 - 2032

Genome-wide associations for birth weight and correlations with adult disease.

Horikoshi M. et al, (2016), Nature, 538, 248 - 252

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals.

Ehret GB. et al, (2016), Nat Genet, 48, 1171 - 1184

Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension.

Surendran P. et al, (2016), Nat Genet, 48, 1151 - 1161

Variation in the glucose transporter gene SLC2A2 is associated with glycemic response to metformin.

Zhou K. et al, (2016), Nat Genet, 48, 1055 - 1059

The genetic architecture of type 2 diabetes.

Fuchsberger C. et al, (2016), Nature, 536, 41 - 47

Type 2 Diabetes Risk Variants in PAM Reduce Chromogranin A-mediated Insulin Availability and Secretion from Beta Cells

Raimondo A. et al, (2016), DIABETES, 65, A52 - A52

Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci.

Gaulton KJ. et al, (2015), Nat Genet, 47, 1415 - 1425

Using genomic information to differentiate diabetes aetiology in young-adult onset diabetes

Kavvoura FK. et al, (2015), DIABETOLOGIA, 58, S22 - S22

Discovery and Fine-Mapping of Glycaemic and Obesity-Related Trait Loci Using High-Density Imputation.

Horikoshi M. et al, (2015), PLoS Genet, 11

Using genomic information to differentiate aetiology in young adult onset diabetes

Kavvoura FK. et al, (2015), DIABETIC MEDICINE, 32, 18 - 18

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