Publications — Radcliffe Department of Medicine

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The age-dependent development of abnormal cardiac metabolism in the peroxisome proliferator-activated receptor α-knockout mouse.

Dodd MS. et al, (2024), Atherosclerosis

Modulating Cardiac Energetics in Cardio-Metabolic Syndromes: A mechanistic, hyperpolarized MR Trial of Ninerafaxstat Treatment

Hundertmark MJ. et al, (2024)

Compartment-based reconstruction of acquisition-weighted 31P cardiac MRSI reduces sensitivity to cardiac motion and scan planning

Tyler A. et al, (2024), Frontiers in Physiology, 14

The effect of and correction for through-slice dephasing on 2D gradient-echo double angle B 1 + mapping.

Belsley G. et al, (2023), Magn Reson Med

Hyperpolarized Carbon 13 MRI: Clinical Applications and Future Directions in Oncology.

Deen SS. et al, (2023), Radiol Imaging Cancer, 5

Compartment‐based Reconstruction of 3D Acquisition‐Weighted 31 P Cardiac MRSI at 7T ‐ a Reproducibility Study

Tyler A. et al, (2023), NMR in Biomedicine

RF coil design for accurate parallel imaging on 13 C MRSI using 23 Na sensitivity profiles.

Sanchez-Heredia JD. et al, (2022), Magn Reson Med, 88, 1391 - 1405

Acidic environments trigger intracellular H+-sensing FAK proteins to re-balance sarcolemmal acid-base transporters and auto-regulate cardiomyocyte pH.

Wilson AD. et al, (2021), Cardiovasc Res

Activation of HIF1α Rescues the Hypoxic Response and Reverses Metabolic Dysfunction in the Diabetic Heart.

Sousa Fialho MDL. et al, (2021), Diabetes, 70, 2518 - 2531

Proof-of-Principle Demonstration of Direct Metabolic Imaging Following Myocardial Infarction Using Hyperpolarized 13C CMR.

Apps A. et al, (2021), JACC Cardiovasc Imaging, 14, 1285 - 1288

Rapid, B1 -insensitive, dual-band quasi-adiabatic saturation transfer with optimal control for complete quantification of myocardial ATP flux.

Miller JJ. et al, (2021), Magn Reson Med, 85, 2978 - 2991

Hyperpolarized magnetic resonance shows that the anti-ischemic drug meldonium leads to increased flux through pyruvate dehydrogenase in vivo resulting in improved post-ischemic function in the diabetic heart.

Savic D. et al, (2021), NMR Biomed, 34

L-Carnitine Stimulates In Vivo Carbohydrate Metabolism in the Type 1 Diabetic Heart as Demonstrated by Hyperpolarized MRI.

Savic D. et al, (2021), Metabolites, 11

BH4 Increases nNOS Activity and Preserves Left Ventricular Function in Diabetes.

Carnicer R. et al, (2021), Circ Res, 128, 585 - 601

Hyperpolarized 13 C magnetic resonance imaging for noninvasive assessment of tissue inflammation.

Anderson S. et al, (2021), NMR Biomed, 34

Quantifying the effect of dobutamine stress on myocardial Pi and pH in healthy volunteers: A 31 P MRS study at 7T.

Apps A. et al, (2021), Magn Reson Med, 85, 1147 - 1159

A 3D hybrid-shot spiral sequence for hyperpolarized 13 C imaging.

Tyler A. et al, (2021), Magn Reson Med, 85, 790 - 801

Probing hepatic metabolism of [2-13C]dihydroxyacetone in vivo with 1H-decoupled hyperpolarized 13C-MR.

Marco-Rius I. et al, (2021), MAGMA, 34, 49 - 56

Hyperpolarized MR in cardiology: probing the heart of life

Miller JJ. et al, (2021), Advances in Magnetic Resonance Technology and Applications, 217 - 256

Early detection of doxorubicin-induced cardiotoxicity in rats by its cardiac metabolic signature assessed with hyperpolarized MRI.

Timm KN. et al, (2020), Commun Biol, 3

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