Publications — Radcliffe Department of Medicine

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Controversy in mechanotransduction: the role of endothelial cell-cell junctions in fluid shear stress sensing.

X S. et al, (2024), J Cell Sci

Proteostasis and resilience in the mechanically-stressed vascular endothelium

Keen A. et al, (2023), Current Opinion in Physiology, 34

Mechanisms of endothelial flow sensing

Aitken C. et al, (2023), Nature Cardiovascular Research, 2, 517 - 529

Author Correction: The guidance receptor plexin D1 is a mechanosensor in endothelial cells.

Mehta V. et al, (2022), Nature

Eukaryotic initiation factor 6 regulates mechanical responses in endothelial cells.

Keen AN. et al, (2022), J Cell Biol, 221

Mechanical forces regulate endothelial-to-mesenchymal transition and atherosclerosis via an Alk5-Shc mechanotransduction pathway.

Mehta V. et al, (2021), Sci Adv, 7

A key role for the novel coronary artery disease gene JCAD in atherosclerosis via shear stress mechanotransduction.

Douglas G. et al, (2020), Cardiovasc Res, 116, 1863 - 1874

Mechanical Forces and Their Effect on the Ribosome and Protein Translation Machinery.

Simpson LJ. et al, (2020), Cells, 9

The guidance receptor plexin D1 is a mechanosensor in endothelial cells.

Mehta V. et al, (2020), Nature, 578, 290 - 295

Mechanical Regulation of Protein Translation in the Cardiovascular System.

Simpson LJ. et al, (2020), Front Cell Dev Biol, 8

To Fuse or Not to Fuse.

Simpson LJ. and Tzima E., (2018), Arterioscler Thromb Vasc Biol, 38, 1959 - 1960

Haemodynamics Regulate Fibronectin Assembly via PECAM.

Chen Z. et al, (2017), Sci Rep, 7

Cardiovascular disease: A turbulent path to plaque formation.

Mehta V. and Tzima E., (2016), Nature, 540, 531 - 532

The zebrafish homologs of SET/I2PP2A oncoprotein: expression patterns and insights into their physiological roles during development.

Serifi I. et al, (2016), Biochem J, 473, 4609 - 4627

Endothelial Mechanosignaling: Does One Sensor Fit All?

Givens C. and Tzima E., (2016), Antioxid Redox Signal, 25, 373 - 388

Pulling on my heartstrings: mechanotransduction in cardiac development and function.

McCormick ME. and Tzima E., (2016), Curr Opin Hematol, 23, 235 - 242

Vessels With Cingulin Are Leakproof.

Givens C. and Tzima E., (2016), Arterioscler Thromb Vasc Biol, 36, 584 - 585

Cardiac contraction activates endocardial Notch signaling to modulate chamber maturation in zebrafish.

Samsa LA. et al, (2015), Development, 142, 4080 - 4091

Inflammation

Collins C. et al, (2015), Atherosclerosis: Risks, Mechanisms, and Therapies, 43 - 52

Platelet endothelial cell adhesion molecule-1 mediates endothelial-cardiomyocyte communication and regulates cardiac function.

McCormick ME. et al, (2015), J Am Heart Assoc, 4

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