Publications — Radcliffe Department of Medicine

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The chromatin remodeller ATRX facilitates diverse nuclear processes, in a stochastic manner, in both heterochromatin and euchromatin.

Truch J. et al, (2022), Nat Commun, 13

IL-6 effector function of group 2 innate lymphoid cells (ILC2) is NOD2 dependent.

Hardman CS. et al, (2021), Sci Immunol, 6

BET inhibition disrupts transcription but retains enhancer-promoter contact.

Crump NT. et al, (2021), Nat Commun, 12

A blood atlas of COVID-19 defines hallmarks of disease severity and specificity

COvid-19 Multi-omics Blood ATlas (COMBAT) Consortium None. et al, (2021)

Single-cell atlas of colonic CD8+ T cells in ulcerative colitis.

Corridoni D. et al, (2020), Nat Med, 26, 1480 - 1490

Cell-intrinsic depletion of Aml1-ETO-expressing pre-leukemic hematopoietic stem cells by K-Ras activating mutation.

Di Genua C. et al, (2019), Haematologica, 104, 2215 - 2224

Reconstruction of the Global Neural Crest Gene Regulatory Network In Vivo.

Williams RM. et al, (2019), Dev Cell, 51, 255 - 276.e7

Reconstruction of the Global Neural Crest Gene Regulatory Network In Vivo.

Williams RM. et al, (2019), Dev Cell, 51, 255 - 276.e7

Transcriptomic profiling of the myeloma bone-lining niche reveals BMP signalling inhibition to improve bone disease.

Gooding S. et al, (2019), Nat Commun, 10

DOT1L inhibition reveals a distinct subset of enhancers dependent on H3K79 methylation.

Godfrey L. et al, (2019), Nat Commun, 10

Does osteogenic potential of clonal human bone marrow mesenchymal stem/stromal cells correlate with their vascular supportive ability?

Merryweather-Clarke AT. et al, (2018), Stem Cell Res Ther, 9

SCL/TAL1 cooperates with Polycomb RYBP-PRC1 to suppress alternative lineages in blood-fated cells.

Chagraoui H. et al, (2018), Nat Commun, 9

From Pioneer to Repressor: Bimodal foxd3 Activity Dynamically Remodels Neural Crest Regulatory Landscape In Vivo.

Lukoseviciute M. et al, (2018), Dev Cell, 47, 608 - 628.e6

Impact of spliceosome mutations on RNA splicing in myelodysplasia: dysregulated genes/pathways and clinical associations.

Pellagatti A. et al, (2018), Blood, 132, 1225 - 1240

Cutaneous bacterial sensing through group 2 innate lymphoid cell presentation of endogenous CD1a lipid antigens

Hardman C. et al, (2018), BRITISH JOURNAL OF DERMATOLOGY, 178, E403 - E403

Canonical Notch signaling is dispensable for adult steady-state and stress myelo-erythropoiesis.

Duarte S. et al, (2018), Blood, 131, 1712 - 1719

Single-cell analysis reveals the continuum of human lympho-myeloid progenitor cells.

Karamitros D. et al, (2018), Nat Immunol, 19, 85 - 97

CD1a presentation of endogenous antigens by group 2 innate lymphoid cells.

Hardman CS. et al, (2017), Sci Immunol, 2

A Novel Model of Human Hemopoiesis Based on Single Cell Functional and Transcriptional Analysis of Lympho-Myeloid Progenitors

Stoilova B. et al, (2017), BLOOD, 130

Cell-Intrinsic Depletion of AML1-ETO-Positive Pre-Leukemic HSCs By Kras Activating Mutation

Di Genua C. et al, (2017), BLOOD, 130

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