Publications — Radcliffe Department of Medicine

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Reducing hyperglucagonaemia in type 2 diabetes using low-dose glibenclamide: Results of the LEGEND-A pilot study.

Spiliotis II. et al, (2022), Diabetes Obes Metab, 24, 1671 - 1675

Risk of second brain tumour after radiotherapy for pituitary adenoma or craniopharyngioma: a retrospective, multicentre, cohort study of 3679 patients with long-term imaging surveillance.

Hamblin R. et al, (2022), Lancet Diabetes Endocrinol, 10, 581 - 588

Low-dose treatment with sulfonylureas improves hyperglucagonemia after a glucose challenge in HNF1A-MODY individuals and Hnf1a(-/-) mice

Saponaro C. et al, (2022), DIABETOLOGIA, 65, S162 - S162

HNF1A Deficiency Leads to Perturbed Glucagon Secretion in Humans

Saponaro C. et al, (2020), DIABETES, 69

Somatostatin secretion by Na+-dependent Ca2+-induced Ca2+ release in pancreatic delta-cells.

Vergari E. et al, (2020), Nat Metab, 2, 32 - 40

The Use of Empagliflozin and Dulaglutide Improves Metabolic and Glycemia Outcomes in a Real-World Primary Care Setting

Spiliotis I. and Gallen IW., (2020), DIABETES, 69

Loss of ZnT8 function protects against diabetes by enhanced insulin secretion.

Dwivedi OP. et al, (2019), Nat Genet, 51, 1596 - 1606

Insulin inhibits glucagon release by SGLT2-induced stimulation of somatostatin secretion.

Vergari E. et al, (2019), Nat Commun, 10

Electrophysiological properties of human beta-cell lines EndoC-βH1 and -βH2 conform with human beta-cells.

Hastoy B. et al, (2018), Sci Rep, 8

Does Islet Size Really Influence Graft Function After Clinical Islet Transplantation?

Hughes SJ. et al, (2018), Transplantation, 102, 1857 - 1863

α-cell glucokinase suppresses glucose-regulated glucagon secretion.

Basco D. et al, (2018), Nat Commun, 9

δ-cells and β-cells are electrically coupled and regulate α-cell activity via somatostatin.

Briant LJB. et al, (2018), J Physiol, 596, 197 - 215

Loss of ZnT8 function protects against diabetes by enhanced insulin secretion

Dwivedi OP. et al, (2018)

Islet/stem cell transplantation – what's new?

Spiliotis I. and Johnson PRV., (2017), Paediatrics and Child Health (United Kingdom), 27, 181 - 186

Electrophysiological properties of human β-cell lines EndoC-βH1 and -βH2 conform with human β-cells

Hastoy B. et al, (2017)

Glucagon secretion in type 2 diabetes: results of the pilot clinical trial "Low dosE GlibENclamide in Diabetes - part A (LEGEND-A)"

Spiliotis II. et al, (2017), DIABETOLOGIA, 60, S29 - S29

Reversible changes in pancreatic islet structure and function produced by elevated blood glucose.

Brereton MF. et al, (2014), Nat Commun, 5

Reversible changes in pancreatic islet structure and function produced by elevated blood glucose

Brereton MF. et al, (2014), DIABETOLOGIA, 57, S93 - S93

Proceedings of research in clinical practice 2011.

Spiliotis I. et al, (2012), QJM, 105, 593 - 606

The Emery-Dreifuss muscular dystrophy associated-protein emerin is phosphorylated on serine 49 by protein kinase A.

Roberts RC. et al, (2006), FEBS J, 273, 4562 - 4575

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