Publications — Radcliffe Department of Medicine

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Modulating Cardiac Energetics in Cardio-Metabolic Syndromes: A mechanistic, hyperpolarized MR Trial of Ninerafaxstat Treatment

Hundertmark MJ. et al, (2024)

Compartment-based reconstruction of acquisition-weighted 31P cardiac MRSI reduces sensitivity to cardiac motion and scan planning

Tyler A. et al, (2024), Frontiers in Physiology, 14

A Mitochondrial Basis for Heart Failure Progression

Watson WD. et al, (2024), Cardiovascular Drugs and Therapy

A Framework for Predicting X-Nuclei Transmitter Gain Using 1H Signal

Vaeggemose M. et al, (2023), Tomography, 9, 1603 - 1616

How a technique from particle physics could transform MRI

Miller J., (2023), Physics World, 36, 26 - 31

A multivariate blood metabolite algorithm stably predicts risk and resilience to major depressive disorder in the general population.

Radford-Smith DE. et al, (2023), EBioMedicine, 93

Assessment of Cardiac Energy Metabolism, Function, and Physiology in Patients With Heart Failure Taking Empagliflozin: The Randomized, Controlled EMPA-VISION Trial.

Hundertmark MJ. et al, (2023), Circulation, 147, 1654 - 1669

Compartment‐based Reconstruction of 3D Acquisition‐Weighted 31 P Cardiac MRSI at 7T ‐ a Reproducibility Study

Tyler A. et al, (2023), NMR in Biomedicine

Developing a metabolic clearance rate framework as a translational analysis approach for hyperpolarized 13C magnetic resonance imaging.

Grist JT. et al, (2023), Sci Rep, 13

Reversible pH-responsive MRI contrast with paramagnetic polymer micelles.

Ellis CM. et al, (2023), Chem Commun (Camb)

Cardiometabolic risk factors vary with age differently in females and males

Miller JJ. and Heather LC., (2022), Nature Cardiovascular Research

Direct observation of the molecular mechanism underlying protein polymerization.

Hundt N. et al, (2022), Sci Adv, 8

Assessing the effect of anesthetic gas mixtures on hyperpolarized 13 C pyruvate metabolism in the rat brain.

Healicon R. et al, (2022), Magn Reson Med, 88, 1324 - 1332

Functional and Metabolic Imaging in Heart Failure with Preserved Ejection Fraction: Promises, Challenges, and Clinical Utility.

Burrage MK. et al, (2022), Cardiovasc Drugs Ther

Acute intermittent hypoxia drives hepatic de novo lipogenesis in humans and rodents.

Hazlehurst JM. et al, (2022), Metabol Open, 14

Concentration-dependent effects of dichloroacetate in type 2 diabetic hearts assessed by hyperpolarized [1-13 C]-pyruvate magnetic resonance imaging.

Hansen ESS. et al, (2022), NMR Biomed, 35

The effects of endogenously- and exogenously-induced hyperketonemia on exercise performance and adaptation.

Dearlove DJ. et al, (2022), Physiol Rep, 10

Promoting high T2 contrast in Dy-doped MSNs through Curie effects.

Ellis CM. et al, (2022), J Mater Chem B, 10, 302 - 305

A phase 2a trial investigating ninerafaxstat - a novel cardiac mitotrope for the treatment of diabetic cardiomyopathy (IMPROVE-DiCE)

Hundertmark M. et al, (2022), EUROPEAN HEART JOURNAL, 43, 246 - 246

Acidic environments trigger intracellular H+-sensing FAK proteins to re-balance sarcolemmal acid-base transporters and auto-regulate cardiomyocyte pH.

Wilson AD. et al, (2021), Cardiovasc Res

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