Publications — Radcliffe Department of Medicine

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A repair pathway lost in multiple sclerosis provides a new drug opportunity.

Jensen LT. et al, (2024), Nat Immunol, 25, 385 - 386

Antibody agonists trigger immune receptor signaling through local exclusion of receptor-type protein tyrosine phosphatases.

Lippert AH. et al, (2024), Immunity, 57, 256 - 270.e10

Ancient DNA reveals evolutionary origins of autoimmune diseases.

Barrie W. et al, (2024), Nat Rev Immunol

Elevated genetic risk for multiple sclerosis emerged in steppe pastoralist populations.

Barrie W. et al, (2024), Nature, 625, 321 - 328

The selection landscape and genetic legacy of ancient Eurasians.

Irving-Pease EK. et al, (2024), Nature, 625, 312 - 320

Allosteric TYK2 inhibition: redefining autoimmune disease therapy beyond JAK1-3 inhibitors.

Jensen LT. et al, (2023), EBioMedicine, 97

Mouse fetal growth restriction through parental and fetal immune gene variation and intercellular communications cascade.

Kaur G. et al, (2022), Nat Commun, 13

Identification of early neurodegenerative pathways in progressive multiple sclerosis.

Kaufmann M. et al, (2022), Nat Neurosci

The immunology of multiple sclerosis.

Attfield KE. et al, (2022), Nat Rev Immunol

MOG antibody-associated disease after vaccination with ChAdOx1 nCoV-19.

Francis A. et al, (2022), Lancet Neurol, 21, 217 - 218

Inflammation-related plasma and CSF biomarkers for multiple sclerosis.

Huang J. et al, (2020), Proc Natl Acad Sci U S A

A novel neurodegenerative spectrum disorder in patients with MLKL deficiency.

Faergeman SL. et al, (2020), Cell Death Dis, 11

Identifying cross-disease components of genetic risk across hospital data in the UK Biobank.

Cortes A. et al, (2019), Nat Genet

B cell tolerance and antibody production to the celiac disease autoantigen transglutaminase 2.

du Pré MF. et al, (2019), The Journal of experimental medicine

A plasmid-encoded peptide from Staphylococcus aureus induces anti-myeloperoxidase nephritogenic autoimmunity.

Ooi JD. et al, (2019), Nat Commun, 10

Systematic classification of shared components of genetic risk for common human diseases

Cortes A. et al, (2018)

HLA variation and disease.

Dendrou CA. et al, (2018), Nat Rev Immunol, 18, 325 - 339

The Human Cell Atlas.

Regev A. et al, (2017), Elife, 6

Immunomodulation in multiple sclerosis: promises and pitfalls.

Dendrou CA. and Fugger L., (2017), Curr Opin Immunol, 49, 37 - 43

Bayesian analysis of genetic association across tree-structured routine healthcare data in the UK Biobank.

Cortes A. et al, (2017), Nat Genet, 49, 1311 - 1318

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