Genetic determinants of monocyte splicing are enriched for disease susceptibility loci including for COVID-19
Preprint
Fairfax B. et al, (2024)
High-throughput mass spectrometry maps the sepsis plasma proteome and differences in patient response.
Journal article
Mi Y. et al, (2024), Sci Transl Med, 16
Characterization of the genetic determinants of context-specific DNA methylation in primary monocytes.
Journal article
Gilchrist JJ. et al, (2024), Cell Genom
Genome-wide characterization of circulating metabolic biomarkers.
Journal article
Karjalainen MK. et al, (2024), Nature
Translating the potential of the urine steroid metabolome to stage NAFLD (TrUSt-NAFLD): study protocol for a multicentre, prospective validation study.
Journal article
Miller H. et al, (2024), BMJ Open, 14
MLX plays a key role in lipid and glucose metabolism in humans: evidence from in vitro and in vivo studies
Journal article
NAGARAJAN S. et al, (2023), Metabolism: clinical and experimental
Type 2 Diabetes risk alleles in Peptidyl-glycine Alpha-amidating Monooxygenase influence GLP-1 levels and response to GLP-1 Receptor Agonists.
Journal article
Umapathysivam MM. et al, (2023), medRxiv
Polygenic risk in Type III hyperlipidaemia and risk of cardiovascular disease: An epidemiological study in UK Biobank and Oxford Biobank.
Journal article
Pieri K. et al, (2022), Int J Cardiol
A saturated map of common genetic variants associated with human height.
Journal article
Yengo L. et al, (2022), Nature, 610, 704 - 712
High-throughput mass spectrometry maps the sepsis plasma proteome and differences in response
Preprint
Mi Y. et al, (2022)
A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids.
Journal article
Ramdas S. et al, (2022), Am J Hum Genet, 109, 1366 - 1387
TCF7L2 plays a complex role in human adipose progenitor biology, which might contribute to genetic susceptibility to type 2 diabetes.
Journal article
Verma M. et al, (2022), Metabolism, 133
HOTAIR interacts with PRC2 complex regulating the regional preadipocyte transcriptome and human fat distribution.
Journal article
Kuo F-C. et al, (2022), Cell Rep, 40
The Arg82Cys Polymorphism of the Protein Nepmucin Implies a Role in HDL Metabolism.
Journal article
Metz S. et al, (2022), J Endocr Soc, 6
Apolipoprotein A-V is a potential target for treating coronary artery disease: evidence from genetic and metabolomic analyses.
Journal article
Ibi D. et al, (2022), J Lipid Res
The associations between body fat distribution and bone mineral density in the Oxford Biobank: a cross sectional study.
Journal article
Hilton C. et al, (2021), Expert Rev Endocrinol Metab, 1 - 7
The power of genetic diversity in genome-wide association studies of lipids.
Journal article
Graham SE. et al, (2021), Nature, 600, 675 - 679
Higher thyrotropin leads to unfavorable lipid profile and somewhat higher cardiovascular disease risk: evidence from multi-cohort Mendelian randomization and metabolomic profiling.
Journal article
van Vliet NA. et al, (2021), BMC Med, 19
The trans-ancestral genomic architecture of glycemic traits.
Journal article
Chen J. et al, (2021), Nat Genet, 53, 840 - 860
Triglyceride-lowering LPL alleles combined with LDL-C-lowering alleles are associated with an additively improved lipoprotein profile.
Journal article
Ibi D. et al, (2021), Atherosclerosis