Publications — Radcliffe Department of Medicine

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The endoplasmic reticulum plays a key role in α-cell intracellular Ca2+ dynamics and glucose-regulated glucagon secretion in mouse islets.

Acreman S. et al, (2024), iScience, 27

PRMT5 activates lipid metabolic reprogramming via MYC contributing to the growth and survival of mantle cell lymphoma.

Liang J-H. et al, (2024), Cancer Lett, 591

Investigation of fatty acid metabolism in chronic lymphocytic leukemia to guide clinical outcome and therapy.

Pan B. et al, (2024), Ann Hematol, 103, 1241 - 1254

Whole transcriptome sequencing analyses of islets reveal ncRNA regulatory networks underlying impaired insulin secretion and increased β-cell mass in high fat diet-induced diabetes mellitus.

Ma J. et al, (2024), PLoS One, 19

GLP-1 metabolite GLP-1(9-36) is a systemic inhibitor of mouse and human pancreatic islet glucagon secretion.

Gandasi NR. et al, (2023), Diabetologia

25-Hydroxy vitamin D deficiency is an inferior predictor of peripheral T-cell lymphomas.

Shen H-R. et al, (2023), Annals of hematology

Genetic lineage tracing identifies adaptive mechanisms of pancreatic islet β cells in various mouse models of diabetes with distinct age of initiation.

Fu Q. et al, (2023), Science China. Life sciences

α-cell electrophysiology and the regulation of glucagon secretion.

Gao R. et al, (2023), J Endocrinol, 258

MYC-induced cytidine metabolism regulates survival and drug resistance via cGas-STING pathway in mantle cell lymphoma.

Liang J-H. et al, (2023), Br J Haematol, 202, 550 - 565

Restored UBE2C expression in islets promotes β-cell regeneration in mice by ubiquitinating PER1.

Jiang H. et al, (2023), Cell Mol Life Sci, 80

Low T3 syndrome as a predictor of poor prognosis in peripheral T-cell lymphomas.

Li W. et al, (2023), Clin Transl Oncol

Low Serum Cholesterol Level Is a Significant Prognostic Factor That Improves CLL-IPI in Chronic Lymphocytic Leukaemia.

Gao R. et al, (2023), Int J Mol Sci, 24

Low T3 syndrome as a predictor of poor outcomes in patients with follicular lymphoma.

Xue L-G. et al, (2023), Ann Hematol, 102, 851 - 862

Single-cell RNA sequencing combined with single-cell proteomics identifies the metabolic adaptation of islet cell subpopulations to high-fat diet in mice.

Fu Q. et al, (2023), Diabetologia, 66, 724 - 740

Loss of electrical beta to delta cell coupling underlies impaired hypoglycaemia-induced glucagon secretion in type 1 diabetes

Gao R. et al, (2023), DIABETOLOGIA, 66, S43 - S43

Phosphoproteome reveals molecular mechanisms of aberrant rhythm in neurotransmitter-mediated islet hormone secretion in diabetic mice.

He Y. et al, (2022), Clin Transl Med, 12

Antecedent hypoglycaemia enhances intra-islet α-δ-cell paracrine feedback loop to impair α-cell glucagon secretion

Gao R. et al, (2022), DIABETOLOGIA, 65, S56 - S56

Circulating microRNA‑135a‑3p in serum extracellular vesicles as a potential biological marker of non‑alcoholic fatty liver disease.

Jiang H. et al, (2021), Mol Med Rep, 24

Temporal metabolic and transcriptomic characteristics crossing islets and liver reveal dynamic pathophysiology in diet-induced diabetes.

Gao R. et al, (2021), iScience, 24

δ-Cells: The Neighborhood Watch in the Islet Community.

Gao R. et al, (2021), Biology (Basel), 10

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