Publications — Radcliffe Department of Medicine

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Structure of a fully assembled γδ T-cell antigen receptor.

Gully BS. et al, (2024), Nature

Antibody agonists trigger immune receptor signaling through local exclusion of receptor-type protein tyrosine phosphatases.

Lippert AH. et al, (2024), Immunity, 57, 256 - 270.e10

Single-cell measurements of two-dimensional binding affinity across cell contacts.

Chouliara M. et al, (2021), Biophys J, 120, 5032 - 5040

Trapping or slowing the diffusion of T cell receptors at close contacts initiates T cell signaling.

Chen KY. et al, (2021), Proc Natl Acad Sci U S A, 118

The Costs of Close Contacts: Visualizing the Energy Landscape of Cell Contacts at the Nanoscale.

Kulenkampff K. et al, (2020), Biophys J

Inside-out mechanisms of CD6 signaling: cytoplasmic and extracellular interactions impact on T cell activation

Santos RF. et al, (2019), EUROPEAN JOURNAL OF IMMUNOLOGY, 49, 346 - 347

Investigation into how T cells trigger on various surfaces

Dam T. et al, (2019), EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS, 48, S190 - S190

Single cell measurements of protein affinity in contacting cells

Chouliara M. et al, (2019), EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS, 48, S190 - S190

The Interplay of Immune Cell Proteins Affects the Orientation, Organisation and Affinity within a Cell -Cell

Junghans V. et al, (2019), EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS, 48, S191 - S191

A cell topography-based mechanism for ligand discrimination by the T cell receptor.

Fernandes RA. et al, (2019), Proc Natl Acad Sci U S A

Constraints on GPCR Heterodimerization Revealed by the Type-4 Induced-Association BRET Assay.

Felce JH. et al, (2019), Biophys J, 116, 31 - 41

Measuring GPCR Stoichiometry Using Types-1, -2, and -3 Bioluminescence Resonance Energy Transfer-Based Assays.

Felce JH. et al, (2019), Methods Mol Biol, 1947, 183 - 197

CD45 exclusion- and cross-linking-based receptor signaling together broaden FcεRI reactivity.

Felce JH. et al, (2018), Sci Signal, 11

LAG-3: a very singular immune checkpoint.

Lui Y. and Davis SJ., (2018), Nat Immunol, 19, 1278 - 1279

Reconstitution of immune cell interactions in free-standing membranes.

Jenkins E. et al, (2018), J Cell Sci, 132

Hydrodynamic trapping measures the interaction between membrane-associated molecules.

Junghans V. et al, (2018), Sci Rep, 8

Single-Molecule Light-Sheet Imaging of Suspended T Cells.

Ponjavic A. et al, (2018), Biophys J, 114, 2200 - 2211

Monomeric TCRs drive T cell antigen recognition.

Brameshuber M. et al, (2018), Nat Immunol, 19, 487 - 496

Monomeric TCRs drive T cell antigen recognition

Brameshuber M. et al, (2018), NATURE IMMUNOLOGY, 19, 487 - +

Capturing resting T cells: the perils of PLL.

Santos AM. et al, (2018), Nat Immunol, 19, 203 - 205

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