Targeted genetic therapies for inherited disorders that affect both cardiac and skeletal muscle.
Psaras Y. and Toepfer CN., (2023), Exp Physiol
Comparing the effects of chemical Ca2+ dyes and R-GECO on contractility and Ca2+ transients in adult and human iPSC cardiomyocytes.
Robinson P. et al, (2023), J Mol Cell Cardiol, 180, 44 - 57
Mechanism based therapies enable personalised treatment of hypertrophic cardiomyopathy.
Margara F. et al, (2022), Sci Rep, 12
CalTrack: High-Throughput Automated Calcium Transient Analysis in Cardiomyocytes.
Psaras Y. et al, (2021), Circ Res, 129, 326 - 341
Combining human-based in silico and in vitro models of inherited cardiac diseases for drug safety and efficacy evaluation
Margara F. et al, (2021), JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS, 111
Defining Diverse Disease Pathomechanisms Across Thick And Thin Filament Hypertrophic Cardiomyopathy Variants
Toepfer C. et al, (2021), CIRCULATION RESEARCH, 129