Publications — Radcliffe Department of Medicine

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Targeted genetic therapies for inherited disorders that affect both cardiac and skeletal muscle.

Psaras Y. and Toepfer CN., (2023), Exp Physiol

Comparing the effects of chemical Ca2+ dyes and R-GECO on contractility and Ca2+ transients in adult and human iPSC cardiomyocytes.

Robinson P. et al, (2023), J Mol Cell Cardiol, 180, 44 - 57

Mechanism based therapies enable personalised treatment of hypertrophic cardiomyopathy.

Margara F. et al, (2022), Sci Rep, 12

Human iPSC-CMs and in-silico technologies define mechanisms and accelerate targeted pharmacogenetics in hypertrophic cardiomyopathy

Margara F. et al, (2022)

CalTrack: High-Throughput Automated Calcium Transient Analysis in Cardiomyocytes.

Psaras Y. et al, (2021), Circ Res, 129, 326 - 341

Combining human-based in silico and in vitro models of inherited cardiac diseases for drug safety and efficacy evaluation

Margara F. et al, (2021), JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS, 111

Defining Diverse Disease Pathomechanisms Across Thick And Thin Filament Hypertrophic Cardiomyopathy Variants

Toepfer C. et al, (2021), CIRCULATION RESEARCH, 129

Include forthcoming?