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Desborough Group: Platelet disorders and transfusion

  • Nuffield Division of Clinical Laboratory Sciences
3D render of blood cells on abstract background © Image by kjpargeter on Freepik

The overarching aim of the group is to develop and trial new treatments for platelet disorders and finding alternatives to platelet transfusion.

  1. This includes trials of reversing antiplatelet drugs in intracerebral haemorrhage
  2. Optimising treatment of fetal and neonatal alloimmune thrombocytopenia (FNAIT)
  3. Clinical trials in transfusion medicine and immunohaematology [thrombotic thrombocytopenic purpura (TTP), immune thrombocytopenia (ITP), warm autoimmune haemolytic anaemia (wAIHA), cold agglutinin disease (CAD)]
  4. Developing the evidence base for platelet transfusion and alternatives to transfusion

Our team

Selected publications

Collaborators

  • Professor Nikola Sprigg (University of Nottingham)
  • Dr Beth Psaila
  • Dr Lise Estcourt 
  • Dr Sue Pavord (University of Oxford)
  • Professor Samira Lakhal-Littleton (University of Oxford)
  • Dr Alex Bye (University of Reading)
  • Susan Brunskill (Systemic Reviews Initiative, NHS Blood and Transplant)

Related research themes

We are committed to translating our innovative research into clinical benefit. From new methods of diagnosing chronic conditions, to finding the latest treatments for diabetes, cancer, heart disease, stroke and rare diseases, our department is involved in hundreds of clinical studies every year.
Clinical Studies and Trials