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Found 10 matches for
Holloway Group: Microfluidic Neurological Models (MNM)
Investigative Medicine Division
The Oxford MNM group focuses on developing in vitro models for neurological disease. Employing micro-fabrication techniques to define channels and features in cell culture devices at the scale of the cell and below, opens up the opportunity to shape cellular microenvironments to better reflect those found in the body. Our work uses these techniques and induced pluripotent stem cell (iPSC) technologies to create human cell culture models of the brain with the aim of enabling new possibilities to study neurovascular disease and improve drug discovery.
Koohy Group: Machine Learning and Integrative Approaches in Immunology
Investigative Medicine Division MRC Translational Immune Discovery Unit MRC Weatherall Institute of Molecular Medicine
We would like to understand the functional and molecular mechanisms of the immune system in various immunologically important conditions such as cancer, infection, autoimmune disease as well as ageing. We have a special interest in computational cancer immunotherapy such as antigen presentation, neo-antigen identification and T cell recognition of neo-antigens as well as interrogating the immune response to personalized vaccines from neo-antigens.
Townsend Group: Molecular Immunology
Investigative Medicine Division MRC Translational Immune Discovery Unit MRC Weatherall Institute of Molecular Medicine
Jackson Group: Lymphatic Trafficking Research Group
Investigative Medicine Division MRC Translational Immune Discovery Unit MRC Weatherall Institute of Molecular Medicine
We focus on the mechanisms controlling the migration of leucocytes and tumour cells via lymph in health and disease.
Davis Group: T-cell Biology
Investigative Medicine Division MRC Translational Immune Discovery Unit MRC Weatherall Institute of Molecular Medicine
We are interested in how lymphocytes decide to mount immune responses against, for example, tumours. This involves trying to understanding how leukocyte receptors, such as the T-cell receptor and immune checkpoints, are triggered.
Buchan Group: Laboratory of Cerebral Ischemia
Investigative Medicine Division
The Laboratory of Cerebral Ischemia is a pre-clinical research group aiming to discover both the mechanisms which underlie cell death in stroke and to develop novel strategies to reduce this.
Skin Immunology Group
Investigative Medicine Division MRC Translational Immune Discovery Unit MRC Weatherall Institute of Molecular Medicine
The aim of the group is to understand, at the molecular and cellular level, the role of human cutaneous immune responses in mechanisms of disease, treatment and vaccination. We have a particular focus on T cells which recognise inflammatory lipids presented by CD1a. As well as contributing to an understanding of disease pathogenesis, we aim to translate our findings to changes in clinical practice.
Buchan Group: Responsible Research and Innovation
Investigative Medicine Division
We are focusing on how to make research and innovation relevant to society, sustainable and fair for everyone.
Rehwinkel Group: Nucleic Acid Sensing
Investigative Medicine Division MRC Translational Immune Discovery Unit MRC Weatherall Institute of Molecular Medicine
Drakesmith Group: Iron and Immunity
Investigative Medicine Division MRC Translational Immune Discovery Unit MRC Weatherall Institute of Molecular Medicine
We are investigating how iron and anaemia influence immunity and infectious diseases. Our research inspires treatments that control iron physiology to benefit the host at the expense of pathogens.